During the First World War, scientific knowledge about toxic chemicals and gases was applied to warfare. The severe human consequences helped drive later international controls.
The 1925 Geneva Protocol prohibited the use in war of chemical and biological weapons. Later, the Chemical Weapons Convention established broader international prohibitions and verification relating to chemical weapons.
This example shows that scientific knowledge can be used in ways that create major ethical, environmental, social and economic harms, and that societies may respond through laws and treaties.